Posts Tagged ‘psychiatry’
“It’s peculiar. It’s special. There’s very little of it, but it has this pivotal role in the universe.”*…
One of the oldest, scarcest elements in the universe has given us treatments for mental illness, ovenproof casserole dishes, and electric cars. Increasingly, our response to climate change seems to depend on it. But how much do we really know about lithium? Jacob Baynham explains…
The universe was born small, unimaginably dense and furiously hot. At first, it was all energy contained in a volume of space that exploded in size by a factor of 100 septillion in a fraction of a second. Imagine it as a single cell ballooning to the size of the Milky Way almost instantaneously. Elementary particles like quarks, photons and electrons were smashing into each other with such violence that no other matter could exist. The primordial cosmos was a white-hot smoothie in a blender.
One second after the Big Bang, the expanding universe was 10 billion degrees Kelvin. Quarks and gluons had congealed to make the first protons and neutrons, which collided over the course of a few minutes and stuck in different configurations, forming the nuclei of the first three elements: two gases and one light metal. For the next 100 million years or so, these would be the only elements in the vast, unblemished fabric of space before the first stars ignited like furnaces in the dark to forge all other matter.
Almost 14 billion years later, on the third rocky planet orbiting a young star in a distal arm of a spiral galaxy, intelligent lifeforms would give names to those first three elements. The two gases: hydrogen and helium. The metal: lithium.
This is the story of that metal, a powerful, promising and somehow still mysterious element on which those intelligent lifeforms — still alone in the universe, as far as they know — have pinned their hopes for survival on a planet warmed by their excesses…
[Baynham tells the story of this remarkable element, the development of it many uses (in psychopharmacology, in materials science, and of course in electronics– especially batteries), the rigors of extracting it for those purposes, and the challenges that its scarcity– and its potency– present…]
… Long before cell phones and climate anxiety and the Tesla Model Y, long before dinosaurs and the first creatures that climbed out of the ocean to walk on land, long before the Earth formed from swirling masses of cosmic matter heavy enough to coalesce, back, way back, to the infant universe, to the dawn of matter itself, there were just three types of atoms — three elements in the blank canvas of space. One of them was lithium. It was light, fragile and extremely reactive, its one outer electron tenuously held in place.
Everything we have done with lithium, all its wondrous applications in energy, industry and psychiatry, somehow hinges on this basic structure, a sort of magic around which we’re increasingly engineering our future. Lightness is usually associated with abundance on the periodic table — almost 99% of the mass of the universe is just the lightest two elements. Lithium, however, is the third lightest element and still mysteriously scarce…
That most elemental of elements: “The Secret, Magical Life of Lithium,” from @JacobBaynham in @noemamag.com.
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As we muse on materials, we might send densely-packed birthday greetings to Philip W. Anderson; he was born on this date in 1923. A theoretical physicist, he shared (with John H. Van Vleck and Sir Nevill F. Mott) the 1977 Nobel Prize for Physics for his research on semiconductors, superconductivity, and magnetism. Anderson made contributions to the theories of localization, antiferromagnetism, symmetry breaking including a paper in 1962 discussing symmetry breaking in particle physics, leading to the development of the Standard Model around 10 years later), and high-temperature superconductivity, and to the philosophy of science through his writings on emergent phenomena. He was a pioneer in the field that he named: condensed matter physics, which has found applications in semiconductor and laserr technology, magnetic storage, liquid crystals, optical fibers, nanotechnology, quantum computing, and biomedicine.
“Don’t let us forget that the causes of human actions are usually immeasurably more complex and varied than our subsequent explanations of them”*…
Further, in a fashion, to yesterday’s post: Patricia Fara explains how the tension between religion and science as arbiters of knowledge came to head in the French Revolution, and how that inspired Lambert Adolphe Jacques Quetelet, a Belgian astronomer, mathematician, statistician, and sociologist, to introduce a radically new way of thinking about human beings:
… God had been forcefully excluded from astronomy during the French Revolution, when Pierre-Simon Laplace rewrote Newton’s ideas to create his deterministic cosmos, in which scientific laws govern every movement of every planet with no need for divine intervention. Inspired by this success, a Belgian astronomer called Alphonse Queteler decided that human societies are also controlled by laws. Each country has its own statistical patterns that remain constant from year to year–suicide and crime rates, for instance–and so Quetelet suggested that an ‘average man’ can consistently encapsulate a nation’s characteristics. Politicians should, Quetelet prescribed, operate like social physicists and try to improve average behaviour rather than worry about extreme anomalies. For him, variations from the statistical mean were–like planetary wobbles–imperfections to be smoothed out so that overall progress could be ensured.
Quetelet had introduced a radically new way of thinking about human beings. As one of his admirers put it, ‘Man is seen to be an enigma only as an individual, in mass, he is a mathematical problem.’ Quetelet’s successors took his ideas in many different directions. For one thing, his work was valuable politically because it could be interpreted in different ways. While conservatives insisted that little could be done to alter the current system, radicals accused governments of impeding the natural course of progress, and Utopians–such as Karl Marx–envisaged harmonious societies governed by nature’s own laws guaranteeing improvement. Data collection projects proliferated, and statisticians searched for laws governing every aspect of life, ranging from the weather to the growth of civilization, from stock market fluctuations to the incidence of disease. Many scientists took their ideas from Quetelet rather than from abstract textbooks–but they added their own twist. Whereas Quetelet regarded individual deviations from the norm as errors to be eliminated, scientists set out to study how variations occur…
An excerpt from Fara’s Science: A Four Thousand Year History, via the invaluable Delanceyplace.com (@delanceyplace): “God, Science, and Data.”
* Fyodor Dostoevsky, The Idiot
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As we focus on frames, we might spare a thought for a man who kept his eye on the individual, Wilhelm Reich. A medical doctor and psychoanalyst, he was a member of the second generation of analysts after Sigmund Freud. Reich developed a system of psychoanalysis concentrating on overall character structure, rather than on individual neurotic symptoms. His early work on psychoanalytic technique was overshadowed by his involvement in the sexual-politics movement and by “orgonomy,” a pseudoscientific system he developed. He also built a device he called a cloud buster, with which he claimed he could manipulate the weather by manipulating the “orgone” in the atmosphere. Reich’s claims aroused much controversy; and he was taken to court for fraud by the Food and Drug Administration (FDA). The court ordered his books and research burned and his equipment destroyed. Reich was sentenced to prison where he died of heart failure on this date in 1957.
“Psychedelic experiences are notoriously hard to render in words”*…
… to categorize them, even harder. But Josie Kins (@Josikinz) and her colleagues at Effect Index are putting in the work…
The Subjective Effect Index is a set of articles designed to serve as a comprehensive catalogue and reference for the range of subjective effects that may occur under the influence of psychoactive substances and other psychonautic techniques.
The effects listed here are accompanied by detailed descriptions on the subjective experiences of them. They are written in a consistent and formal writing style that avoids the use of flowery metaphors or analogy; instead, they strive to use simple and accessible language. This is done with the hope that they will eventually serve as a universal terminology set that enables people to better communicate and share experiences that are, by nature, difficult to convey.
The Index is separated into 233 effects, which are organised into categories based on the senses they affect and their behavior. Many of these are further broken down into leveling systems, subcomponents, and style variations that may occur across different substances. Detailed image, video, and audio replications [like the one above] have been included wherever possible to supplement text-based descriptions…
Stanislav Grof, M.D has argued that “LSD is a catalyst or amplifier of mental processes. If properly used it could become something like the microscope or telescope of psychiatry.” Effects Index is attempting to build a database to help that process along.
* Michael Pollan
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As we tackle the taxonomy of trips, we might recall that it was on this date in 1842 that (modern) anesthesia was used for the first time in an operation– by Dr. Crawford Long. Long, a physician and a pharmacist, used diethyl ether in the removal of a tumor from the neck of James Venable in Jefferson, GA; given success with Venable, Long then used ether in other surgeries and in childbirths. He published the results of these trials in 1848 in The Southern Medical and Surgical Journal (an original copy of which is held in the U.S. National Library of Medicine).
It’s cool that Long is the subject of one of the two statues representing Georgia in the crypt of the U.S. Capitol. It’s cooler that Long was the cousin of Doc Holliday.

Crawford Long (source)
“If names be not correct, language is not in accordance with the truth of things”*…
What’s in a name?…
The goal of this article is to promote clear thinking and clear writing among students and teachers of psychological science by curbing terminological misinformation and confusion. To this end, we present a provisional list of 50 commonly used terms in psychology, psychiatry, and allied fields that should be avoided, or at most used sparingly and with explicit caveats. We provide corrective information for students, instructors, and researchers regarding these terms, which we organize for expository purposes into five categories: inaccurate or misleading terms, frequently misused terms, ambiguous terms, oxymorons, and pleonasms. For each term, we (a) explain why it is problematic, (b) delineate one or more examples of its misuse, and (c) when pertinent, offer recommendations for preferable terms. By being more judicious in their use of terminology, psychologists and psychiatrists can foster clearer thinking in their students and the field at large regarding mental phenomena…
From “a gene for” through “multiple personality disorder” and “scientific proof” to “underlying biological dysfunction”: “Fifty psychological and psychiatric terms to avoid: a list of inaccurate, misleading, misused, ambiguous, and logically confused words and phrases.”
[TotH to @BoingBoing, whence the photo above]
* Confucius, The Analects
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As we speak clearly, we might send carefully-worded birthday greetings to Francois-Marie Arouet, better known as Voltaire; he was born on this date in 1694. The Father of the Age of Reason, he produced works in almost every literary form: plays, poems, novels, essays, and historical and scientific works– more than 2,000 books and pamphlets (and more than 20,000 letters). He popularized Isaac Newton’s work in France by arranging a translation of Principia Mathematica to which he added his own commentary.
A social reformer, Voltaire used satire to criticize the intolerance, religious dogma, and oligopolistic privilege of his day, perhaps nowhere more sardonically than in Candide.

“Biology gives you a brain. Life turns it into a mind.”*…

I have a confession. As a physicist and psychiatrist, I find it difficult to engage with conversations about consciousness. My biggest gripe is that the philosophers and cognitive scientists who tend to pose the questions often assume that the mind is a thing, whose existence can be identified by the attributes it has or the purposes it fulfils.
But in physics, it’s dangerous to assume that things ‘exist’ in any conventional sense. Instead, the deeper question is: what sorts of processes give rise to the notion (or illusion) that something exists? For example, Isaac Newton explained the physical world in terms of massive bodies that respond to forces. However, with the advent of quantum physics, the real question turned out to be the very nature and meaning of the measurements upon which the notions of mass and force depend – a question that’s still debated today.
As a consequence, I’m compelled to treat consciousness as a process to be understood, not as a thing to be defined. Simply put, my argument is that consciousness is nothing more and nothing less than a natural process such as evolution or the weather. My favourite trick to illustrate the notion of consciousness as a process is to replace the word ‘consciousness’ with ‘evolution’ – and see if the question still makes sense. For example, the question What is consciousness for? becomes What is evolution for? Scientifically speaking, of course, we know that evolution is not for anything. It doesn’t perform a function or have reasons for doing what it does – it’s an unfolding process that can be understood only on its own terms. Since we are all the product of evolution, the same would seem to hold for consciousness and the self.
My view on consciousness resonates with that of the philosopher Daniel Dennett, who has spent his career trying to understand the origin of the mind. Dennett is concerned with how mindless, mere ‘causes’ (A leads to B) can give rise to the species of mindful ‘reasons’ as we know them (A happens so that B can happen). Dennett’s solution is what he calls ‘Darwin’s dangerous idea’: the insight that it’s possible to have design in the absence of a designer, competence in the absence of comprehension, and reasons (or ‘free-floating rationales’) in the absence of reasoners. A population of beetles that has outstripped another has probably done so for some ‘reason’ we can identify – a favourable mutation which produces a more camouflaging colour, for example. ‘Natural selection is thus an automatic reason-finder, which “discovers” and “endorses” and “focuses” reasons over many generations,’ Dennett writes in From Bacteria to Bach and Back: The Evolution of Minds (2017). ‘The scare quotes are to remind us that natural selection doesn’t have a mind, doesn’t itself have reasons, but is nevertheless competent to perform this “task” of design refinement.’
I hope to show you that nature can drum up reasons without actually having them for herself. In what follows, I’m going to argue that things don’t exist for reasons, but certain processes can nonetheless be cast as engaged in reasoning…
Distinguished neuroscientist and psychiatrist Karl Friston argues that the special trick of consciousness is being able to project action and time into a range of possible futures: “The mathematics of mind-time.”
See also: “How the Brain Creates a Timeline of the Past” (source of the image above).
* Middlesex
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As we get our minds around our minds, we might spare a thought for Oliver Wolf Sacks; he died on this date in 2015. A neurologist, naturalist, historian of science, and author, he had an active clinical practice, but is more widely-remembered for his writing, mostly case studies from his clinical experience and memoir in which which he treats himself as a clinical subject. Awakenings, for example, recounted his experience treating post-encephalitic patients with a new drug (levodopa); it was a best seller that served as the basis of a BBC Discovery documentary and was adapted into a feature film. Widely honored for his prolific work, Sacks was the recipient of the 2001 Lewis Thomas Prize for excellence in scientific writing.






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