(Roughly) Daily

Posts Tagged ‘change

“A new scientific truth does not triumph by convincing its opponents and making them see the light, but rather because its opponents eventually die, and a new generation grows up that is familiar with it”*…

It’s very hard, historian of science Benjamin Breen explains, to understand the implications of a scientific revolution as one is living through it…

2023 is shaping up to be an important year in the history of science. And no, I’m not talking about the reputed room-temperature semiconductor LK-99, which seems increasingly likely to be a dud.

Instead, I’m talking about the discoveries you’ll find in Wikipedia’s list of scientific advances for 2023. Here are some examples:

• January: Positive results from a clinical trial of a vaccine for RSV; OpenAI’s ChatGPT enters wide use.

February: A major breakthrough in quantum computing; announcement of a tiny robot that can clean blood vessels; more evidence for the ability of psychedelics to enhance neuroplasticity; major developments in biocomputers.

• March: OpenAI rolls out GPT-4; continued progress on mRNA vaccines for cancer.

• April: NASA announces astronaut crew who will orbit the moon next year; promising evidence for gene therapy to fight Alzheimer’s.

• May: Scientists use AI to translate brain activity into written words; promising results for a different Alzheimer’s drug; human pangenome sequenced (largely by a team of UCSC researchers — go Banana Slugs!); more good news about the potential of mRNA vaccines for fighting cancer.

And skipping ahead to just the past two weeks:

• nuclear fusion ignition with net energy gain was achieved for the second time

• a radical new approach to attacking cancer tumors entered Phase 1 trials in humans

• and — announced just as I was writing this [in August, 2023] — one of the new crop of weight loss drugs was reported to cut rates of heart attack and stroke in high-risk individuals by 20% (!).

Also in January of 2023: the New York Times asked “What Happened to All of Science’s Big Breakthroughs?”

The headline refers to an article published in Nature which argues that there has been a steady drop in “disruptive” scientific and technological breakthroughs between the years of 1945 and 2010. Basically, it’s a restatement of the concept of a “Great Stagnation” which was proposed by the economist Tyler Cowen in 2011. Though the paper cites everyone from Cowen to Albert Einstein and Isaac Newton, it’s worth noting that it doesn’t cite a single historian of science or technology (unless Alexandre Koyré counts)…

Naturally, as a historian of science and medicine, I think that there really are important things to learn from the history of science and medicine! And what I want to argue for the rest of this post boils down to two specific lessons from that history:

  1. People living through scientific revolutions are usually unaware of them — and, if they are, they don’t think about them in the same way that later generations do.
  2. An apparent slowdown in the rate of scientific innovation doesn’t always mean a slowdown in the impacts of science. The history of the first scientific revolution — the one that began in the famously terrible seventeenth century — suggests that the positive impacts of scientific innovation, in particular, are not always felt by the people living throughthe period of innovation. Periods when the pace of innovation appears to slow down may also be eras when society becomes more capable of benefitting from scientific advances by learning how to mitigate previously unforeseen risks.

[… There follows a fascinating look back at the 1660s– the “original” scientific revolution– at Boyle, Newton, at what they hoped/expected, and at how that differed for what their work and that of their colleagues actually yielded. Then the cautionary tale of Thomas Midgley..]

As we appear to be entering a new era of rapid scientific innovation in the 2020s, it is worth remembering that it often takes decades before the lasting social value of a technical innovation is understood — and decades more before we understand its downsides.

In the meantime, I’m pretty psyched about the cancer drugs…

As Thomas Kuhn observed, “The historian of science may be tempted to exclaim that when paradigms change, the world itself changes with them.”

On the difficulty of knowing the outcomes of a scientific revolution from within it: “Experiencing scientific revolutions: the 1660s and the 2020s,” from @ResObscura.

* Max Planck

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As we try to see, we might spare a thought for William Seward Burroughs; he died on this date in 1898. And inventor who had worked in a bank, he invented the world’s first commercially viable recording adding machine and pioneered of its manufacture. The very successful company that he founded went on to become Unisys, which was instrumental in the development of computing… the implications of which we’re still discovering– and Burroughs surely never saw.

Nor, one reckons, did he imagine that his grandson, William Seward Burroughs II, would become the cultural figure that he did.

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“Nothing is so painful to the human mind as a great and sudden change”*…

If an AI-infused web is the future, what can we learn from the past? Jeff Jarvis has some provocative thoughts…

The Gutenberg Parenthesis—the theory that inspired my book of the same name—holds that the era of print was a grand exception in the course of history. I ask what lessons we may learn from society’s development of print culture as we leave it for what follows the connected age of networks, data, and intelligent machines—and as we negotiate the fate of such institutions as copyright, the author, and mass media as they are challenged by developments such as generative AI. 

Let’s start from the beginning…

In examining the half-millennium of print’s history, three moments in time struck me: 

  • After Johannes Gutenberg’s development of movable type in the 1450s in Europe (separate from its prior invention in China and Korea), it took a half-century for the book as we now know it to evolve out of its scribal roots—with titles, title pages, and page numbers. It took another century, until this side and that of 1600, before there arose tremendous innovation with print: the invention of the modern novel with Cervantes, the essay with Montaigne, a market for printed plays with Shakespeare, and the newspaper.
  • It took another century before a business model for print at last emerged with copyright, which was enacted in Britain in 1710, not to protect authors but instead to transform literary works into tradable assets, primarily for the benefit of the still-developing industry of publishing. 
  • And it was one more century—after 1800—before major changes came to the technology of print: the steel press, stereotyping (to mold complete pages rather than resetting type with every edition), steam-powered presses, paper made from abundant wood pulp instead of scarce rags, and eventually the marvelous Linotype, eliminating the job of the typesetter. Before the mechanization and industrialization of print, the average circulation of a daily newspaper in America was 4,000 (the size of a healthy Substack newsletter these days). Afterwards, mass media, the mass market, and the idea of the mass were born alongside the advertising to support them. 

One lesson in this timeline is that the change we experience today, which we think is moving fast, is likely only the beginning. We are only a quarter century past the introduction of the commercial web browser, which puts us at about 1480 in Gutenberg years. There could be much disruption and invention still ahead. Another lesson is that many of the institutions we assume are immutable—copyright, the concept of creativity as property, mass media and its scale, advertising and the attention economy—are not forever. That is to say that we can reconsider, reinvent, reject, or replace them as need and opportunity present…

Read on for his suggestion for a reinvention of copyright: “Gutenberg’s lessons in the era of AI,” from @jeffjarvis via @azeem in his valuable newsletter @ExponentialView.

* Mary Wollstonecraft Shelley, Frankenstein

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As we contemplate change, we might spare a thought for Jan Hus. A  Czech theologian and philosopher who became a Church reformer, he was burned at the stake as a heretic (for condemning indulgences and the Crusades) on this date in 1415. His teachings (which largely echoed those of Wycliffe) had a strong influence, over a century later, on Martin Luther, helping inspire the Reformation… which was fueled by Gutenberg’s technology, which had been developed and begun to spread in the meantime.

Jan Hus at the stake, Jena codex (c. 1500) source

“It is difficult to predict, especially the future”*…

While perfectly accurate prediction is beyond our ken, it is possible to spot indicators– early warning signs or signals– that the world is headed in one direction or another. BBC R&D Futures is an attempt to do exactly that (in the service of building understanding of the impacts that they might have, right down to the artifacts that they might spawn). For example (from a recent “signals” newsletter):

We are in an era of increasing protests

A number of recent studies tracking and understanding protests and demonstrations around the world are seeing a rise in events. One looking at demonstrations between 2006 and 2020 found that “the number of protest movements around the world had more than tripled in less than 15 years. Every region saw an increase, the study found, with some of the largest protest movements ever recorded.”

Common reasons given for protesting were ‘perceived failure of political systems or representation’, inequality, corruption, lack of action over climate change, and the sense that people’s concerns are not being addressed.

Concerned about the future? A useful source of social, economic, technological, environmental, and political dynamics worthy of attention: BBC R&D Futures.

* Niels Bohr

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As we seek signs, we might recall that it was on this date in 1876 that Melville Bissell patented the first carpet sweeper… one of the innovations (see here, here, e.g.) that revolutionized housekeeping… and with it, modern society.

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Written by (Roughly) Daily

September 19, 2022 at 1:00 am

“Facts are facts and will not disappear on account of your likes”*…

This artist rendering provided by the European South Observatory shows some of the 32 new planets astronomers found outside our solar system

… That said, some facts may morph out from under us. In consideration of “in-between” facts:

When people think of knowledge, they generally think of two sorts of facts: facts that don’t change, like the height of Mount Everest or the capital of the United States, and facts that fluctuate constantly, like the temperature or the stock market close.

But in between there is a third kind: facts that change slowly. These are facts which we tend to view as fixed, but which shift over the course of a lifetime. For example: What is Earth’s population? I remember learning 6 billion, and some of you might even have learned 5 billion. Well, it turns out it’s about 6.8 billion.

Or, imagine you are considering relocating to another city. Not recognizing the slow change in the economic fortunes of various metropolitan areas, you immediately dismiss certain cities. For example, Pittsburgh, a city in the core of the historic Rust Belt of the United States, was for a long time considered to be something of a city to avoid. But recently, its economic fortunes have changed, swapping steel mills for technology, with its job growth ranked sixth in the entire United States.

These slow-changing facts are what I term “mesofacts.” Mesofacts are the facts that change neither too quickly nor too slowly, that lie in this difficult-to-comprehend middle, or meso-, scale. Often, we learn these in school when young and hold onto them, even after they change. For example, if, as a baby boomer, you learned high school chemistry in 1970, and then, as we all are apt to do, did not take care to brush up on your chemistry periodically, you would not realize that there are 12 new elements in the Periodic Table. Over a tenth of the elements have been discovered since you graduated high school! While this might not affect your daily life, it is astonishing and a bit humbling.

For these kinds of facts, the analogy of how to boil a frog is apt: Change the temperature quickly, and the frog jumps out of the pot. But slowly increase the temperature, and the frog doesn’t realize that things are getting warmer, until it’s been boiled. So, too, is it with humans and how we process information. We recognize rapid change, whether it’s as simple as a fast-moving object or living with the knowledge that humans have walked on the moon. But anything short of large-scale rapid change is often ignored. This is the reason we continue to write the wrong year during the first days of January.

Our schools are biased against mesofacts. The arc of our educational system is to be treated as little generalists when children, absorbing bits of knowledge about everything from biology to social studies to geology. But then, as we grow older, we are encouraged to specialize. This might have been useful in decades past, but in our increasingly fast-paced and interdisciplinary world, lacking an even approximate knowledge of our surroundings is unwise.

Updating your mesofacts can change how you think about the world. Do you know the percentage of people in the world who use mobile phones? In 1997, the answer was 4 percent. By 2007, it was nearly 50 percent. The fraction of people who are mobile phone users is the kind of fact you might read in a magazine and quote at a cocktail party. But years later the number you would be quoting would not just be inaccurate, it would be seriously wrong. The difference between a tiny fraction of the world and half the globe is startling, and completely changes our view on global interconnectivity.

Mesofacts can also be fun. Let’s focus for a moment on some mesofacts that can be of vital importance if you’re a child, or parent of a child: those about dinosaurs. Just a few decades ago, dinosaurs were thought to be cold-blooded, slow-witted lizards that walked with their legs splayed out beside them. Now, scientists think that many dinosaurs were warm-blooded and fast-moving creatures. And they even had feathers! Just a few weeks ago we learned about the color patterns of dinosaurs (stripes! with orange tufts!). These facts might not affect how you live your life, but then again, you’re probably not 6 years old. There is another mesofact that is unlikely to affect your daily routine, but might win you a bar bet: the number of planets known outside the solar system. After the first extrasolar planet around an ordinary star made headlines back in 1995, most people stopped paying attention. Well, the number of extrasolar planets is currently over 400. Know this, and the next round won’t be on you.

The fact that the world changes rapidly is exciting, but everyone knows about that. There is much change that is neither fast nor momentous, but no less breathtaking.

Introducing the mesofact: “Warning- Your reality is out of date,” from Samuel Arbesman (@arbesman) who went on to develop this notion in a wonderful book, The Half-Life of Facts. Via @inevernu who notes that the above article, which ran in 2010, contains examples of mesofacts that have already changed again– illustrating Arbesman’s point…

* Jawaharlal Nehru

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As we noodle on knowledge, we might recall that it was on this date in 1642 that the first American college commencement ceremony was held at Harvard College. It was North America’s first taste of non-religious ritual– and was designed to send a clear message to England that its American colonies were a going concern. Still, of the nine seniors graduated, three soon crossed the Atlantic the other way, one to serve as a diplomat for the rebellious Oliver Cromwell and another to study medicine in Italy.

Apropos the piece above, the curriculum followed by those graduates was rather different– was filled with different facts– than those of classes in later centuries.

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Written by (Roughly) Daily

September 23, 2021 at 1:00 am

“When angry, count four. When very angry, swear”*…

Annibale Carracci – The Cyclops Polyphemus (detail)

Anger, like other emotions, has a history.

It is not merely that the causes of anger may change, or attitudes toward its expression. The nature of the emotion itself may alter from one society to another. In classical antiquity, for example, anger was variously viewed as proper to a free citizen (an incapacity to feel anger was regarded as slavish); as an irrational, savage passion that should be extirpated entirely, and especially dangerous when joined to power; as justifiable in a ruler, on the model of God’s righteous anger in the Bible; and as blasphemously ascribed to God, who is beyond all human emotions.

Profound social and cultural changes—the transition from small city-states to the vast reach of the Roman Empire, the adoption of Christianity as the official religion of Rome—lay behind these shifting views, but all the positions had their defenders and were fiercely debated. This rich heritage offers a wealth of insights into the nature of anger, as well as evidence of its social nature; it is not just a matter of biology….

The history of anger– indeed, the very fact that it has a history– sheds light on the elevated emotional climate of today: “Repertoires of Rage.”

* Mark Twain

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As we wrestle with wrath, we might recall that in 1752 in Britain and throughout the British Empire (which included the American colonies) yesterday was September 2. The “jump” was occasioned by a switch from the Julian to the Gregorian calendar, as a product of which almost all of “western civilization” was then on Pope Gregory’s time; Sweden (and Finland) switched the following year.

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Written by (Roughly) Daily

September 14, 2020 at 1:01 am