Posts Tagged ‘Life’
“For you formed my inward parts; you knitted me together in my mother’s womb. I praise you, for I am fearfully and wonderfully made.”*…
DNA is indisputably important to biological development. But, Alfonso Martinez Arias argues, far from being a blueprint for an organism, genes are mere tools used by life’s true expert builders: cells…
… Over the past century, scientists have discovered a material explanation for the source of life, one that needs no divine intervention and provides a thread across eons of time for all beings that exist or have ever existed: deoxyribonucleic acid — DNA. While there is little doubt that genes have something to do with what we are and how we come to be, it is difficult to answer precisely the question of what their exact role in all of this is.
A closer look at how genes work and what they can accomplish, compared to what they are said to achieve, casts doubt on the assertion that the genome in particular contains an “operating manual” for us or any other living creature. When it comes to the creation of organisms, we’ve overlooked — or, more accurately, forgotten — another force. The origin and power of that force are cells.
What makes you and me individual human beings is not a unique set of DNA but instead a unique organization of cells and their activities…
A fascinating essay, adapted from Martinez Arias’ forthcoming book, The Master Builder- How the New Science of the Cell Is Rewriting the Story of Life: “Cells, Not DNA, Are The Master Architects Of Life,” in @NoemaMag.
[Image above: source]
* Psalm 139: 13–14
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As we delve into design, we might send insightful birthday greetings to Ernst Mayr; he was born on this date in 1904. A taxonomist, tropical explorer, ornithologist, philosopher of biology, and historian of science, he is best remembered as one of the 20th century’s leading evolutionary biologists. His work contributed to the conceptual revolution that led to the modern evolutionary synthesis of Mendelian genetics, systematics, and Darwinian evolution, and to the development of the biological species concept.
His theory of peripatric speciation (a more precise form of allopatric speciation which he advanced), based on his work on birds, is still considered a leading mode of speciation, and was the theoretical underpinning for the theory of punctuated equilibrium, proposed by Niles Eldredge and Stephen Jay Gould. Mayr is sometimes credited with inventing modern philosophy of biology, particularly the part related to evolutionary biology, which he distinguished from physics due to evolutionary biology’s introduction of (natural) history into science.
“Not what we have, but what we enjoy, constitutes our abundance”*…
After Aristotle, Hellenic philosophy was dominated by two rival schools of thought, the Stoic (founded by Zeno) and the Epicurean (founded by Epicurus). Over the centuries since, “stoic” has come to mean “self-disciplined indifference to pleasure or (especially) pain as a matter of principle or self-discipline,” while “epicurean” has now conjures “fond of or adapted to luxury or indulgence in sensual pleasures; having luxurious tastes or habits, esp. in eating and drinking.” But as Emily Austin argues in Living for Pleasure, an Epicurean Guide to Life, that’s a bum rap. Stoicism is having a moment. In a review of her new book, Julian Baggini argues that we should consider Epicureanism as well…
No one today would dream of practising the physics, medicine or biology of the ancient Greeks. But their thoughts on how to live remain perennially inspiring. Plato, Aristotle and the Stoics have all had their 21st-century evangelists. Now it is Epicurus’s turn, and his advocate is American philosopher Emily A. Austin.
Living for Pleasure is likely to evoke feelings of deja vu. One reason why “ancient wisdom” is so enduring is that most thinkers came to very similar conclusions on certain key points. Do not be seduced by the shallow temptations of wealth or glory. Pursue what is of real value to you, not what society tells you is most important. Be the sovereign of your desires, not a slave to them. Do not be scared of death, since only the superstitious fear divine punishment.
The more general such claims are, the easier it is to agree. But when we delve into what makes the various philosophers different, what sounds like universal good sense can suddenly seem a bit wacky.
Epicurus’s distinctive feature is his insistence that pleasure is the source of all happiness and is the only truly good thing. Hence the modern use of “epicurean” to mean gourmand. But Epicurus was no debauched hedonist. He thought the greatest pleasure was ataraxia: a state of tranquility in which we are free from anxiety. This raises the suspicion of false advertising – freedom from anxiety may be nice, but few would say it is positively pleasurable.
Still, in a world where even the possibility of missing out inspires fear, freedom from anxiety sounds pretty attractive. How can we get it? Mainly by satisfying the right desires and ignoring the rest. Epicurus thought that desires could be natural or unnatural, and necessary or unnecessary. Our natural and necessary desires are few: healthy food, shelter, clothes, company. As long as we live in a stable, supportive community, they are easy to achieve…
There’s much more in this timely guide to the Greek philosopher – and rival to the Stoics – who saw freedom from anxiety as the ultimate goal: “Living for Pleasure by Emily A Austin – an Epicurean guide to happiness,” from @JulianBaggini in @guardian.
See also: “How to be an Epicurean.”
* Epicurus
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As we contemplate contentment, we might send revelatory birthday greetings to Emanuel Swedenborg; he was born on this date in 1688 (O.S.). At age 53, after a successful career as an inventor and scientist, Sedenborg began to experience dreams and visions, a “spiritual awakening,” in which he received a revelation that Jesus Christ had appointed him to write The Heavenly Doctrine to reform Christianity. According to The Heavenly Doctrine, the Lord had opened Swedenborg’s spiritual eyes so that from then on, he could freely visit heaven and hell to converse with angels, demons and other spirits, and that the Last Judgment had already occurred in 1757 (not by Christ in person but by a revelation from him through the inner, spiritual sense of the Word through Swedenborg), the year before the 1758 publication of De Nova Hierosolyma et ejus doctrina coelesti (Concerning the New Jerusalem and its Heavenly Doctrine). The New Church, also known as Swedenborgianism, is a new religious movement originally founded in 1787 and comprising several historically related Christian denominations that revere Swedenborg’s writings as revelation.
Swedenborg argued against Luther’s concept of salvation through faith-alone (sola-fide in Latin), since he considered both faith and charity necessary for salvation. His thinking influenced a variety of important cultural figures, both writers and artists, including Robert Frost, Johnny Appleseed, William Blake, Jorge Luis Borges, Daniel Burnham, Arthur Conan Doyle, Ralph Waldo Emerson, John Flaxman, George Inness, Henry James Sr., Carl Jung, Immanuel Kant, Honoré de Balzac, Helen Keller, Czesław Miłosz, Joseph Smith, August Strindberg, D. T. Suzuki, and W. B. Yeats.
“What you’re telling is just a story. It isn’t happening anymore”*…
Detail from Senecio by Paul Klee. 1922
Some find it comforting to think of life as a story. Others find that absurd. Galen Strawson weighs in…
‘Each of us constructs and lives a “narrative”,’ wrote the British neurologist Oliver Sacks, ‘this narrative is us’. Likewise the American cognitive psychologist Jerome Bruner: ‘Self is a perpetually rewritten story.’ And: ‘In the end, we become the autobiographical narratives by which we “tell about” our lives.’ Or a fellow American psychologist, Dan P McAdams: ‘We are all storytellers, and we are the stories we tell.’ And here’s the American moral philosopher J David Velleman: ‘We invent ourselves… but we really are the characters we invent.’ And, for good measure, another American philosopher, Daniel Dennett: ‘we are all virtuoso novelists, who find ourselves engaged in all sorts of behaviour… and we always put the best “faces” on it we can. We try to make all of our material cohere into a single good story. And that story is our autobiography. The chief fictional character at the centre of that autobiography is one’s self.’
So say the narrativists. We story ourselves and we are our stories. There’s a remarkably robust consensus about this claim, not only in the humanities but also in psychotherapy. It’s standardly linked with the idea that self-narration is a good thing, necessary for a full human life.
I think it’s false – false that everyone stories themselves, and false that it’s always a good thing. These are not universal human truths – even when we confine our attention to human beings who count as psychologically normal, as I will here. They’re not universal human truths even if they’re true of some people, or even many, or most. The narrativists are, at best, generalising from their own case, in an all-too-human way. At best: I doubt that what they say is an accurate description even of themselves…
Read on for a challenging perspective: “I am not a story,” from @gstrawson in @aeonmag.
* Chuck Palahniuk, Invisible Monsters
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As we rethink retrospection, we might send thoughtful birthday greetings to Samille Diane Friesen– better known by her stage name, Dyan Cannon. She was born on this date in 1937. An actress of accomplishment (she scored a Saturn Award, a Golden Globe Award, three Academy Award nominations, and a star on the Hollywood Walk of Fame), her career began in B movies, but took off after a turn in Bob & Carol & Ted & Alice, for which she received her first Academy Award nomination.
Before her career took off, Cannon was married to Cary Grant for three years and gave birth to his only child, daughter Jennifer. Reluctant to discuss the marriage since their 1968 divorce, Cannon turned down lucrative publishing deals following Grant’s death in 1986. Finally, in 2011, she published a memoir. Dear Cary, which became a New York Times Best Seller.
“So these are the ropes, The tricks of the trade, The rules of the road”*…
Morgan Housel shares a few thing with which he’s come to terms…
Everyone belongs to a tribe and underestimates how influential that tribe is on their thinking.
Most of what people call “conviction” is a willful disregard for new information that might make you change your mind. That’s when beliefs turn dangerous.
History is driven by surprising events but forecasting is driven by obvious ones.
People learn when they’re surprised. Not when they read the right answer, or are told they’re doing it wrong, but when they experience a gap between expectations and reality.
“Learn enough from history to respect one another’s delusions.” -Will Durant
Your personal experiences make up maybe 0.00000001% of what’s happened in the world but maybe 80% of how you think the world works.
Unsustainable things can last longer than you anticipate.
It’s hard to tell the difference between boldness and recklessness, ambition and greed, contrarian and wrong.
There are two types of information: stuff you’ll still care about in the future, and stuff that matters less and less over time. Long-term vs. expiring knowledge. It’s critical to identify which is which when you come across something new.
Small risks are overblown because they’re easy to talk about, big risks are discounted and ignored because they seem preposterous before they arrive.
You can’t believe in risk without also believing in luck because they are fundamentally the same thing—an acknowledgment that things outside of your control can have a bigger impact on outcomes than anything you do on your own.
Once-in-a-century events happen all the time because lots of unrelated things can go wrong. If there’s a 1% chance of a new disastrous pandemic, a 1% chance of a crippling depression, a 1% chance of a catastrophic flood, a 1% chance of political collapse, and on and on, then the odds that something bad will happen next year – or any year – are … pretty good. It’s why Arnold Toynbee says history is “just one damn thing after another.”
Many more affecting aphorisms at: “Little Rules About Big Things,” from @morganhousel @collabfund.
* “Rules Of The Road,” by Cy Coleman and Caroline Leigh (famously recorded by Tony Bennett and Nat King Cole)
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As we ponder precepts, we might send prophylactic birthday greetings to Samuel W. Alderson; he was born on this date in 1914. A physicist and engineer of broad accomplishment, Alderson is probably best remembered as the inventor of the crash test dummy. Alderson created his first dummies in 1956 to test jet ejection seats for the military. But with the passage of the Highway Traffic and Motor Vehicle Safety Act in 1966 (on the heels of the stir created by Ralph Nader’s Unsafe at Any Speed), Alderson found a much broader market. (From the first experiments on car safety in the 1930s, cadavers had been used to assess risk and damage; the dummy had obvious advantages.) Alderson continuously improved his dummies, and later branched out to produce medical “phantoms” for simulations– e.g., synthetic wounds that ooze mock blood.
“Over the long term, symbiosis is more useful than parasitism. More fun, too.”*…
There are many more varieties of minerals on earth than previously believed– and about half of them formed as parts or byproducts of living things…
The impact of Earth’s geology on life is easy to see, with organisms adapting to environments as different as deserts, mountains, forests, and oceans. The full impact of life on geology, however, can be easy to miss.
A comprehensive new survey of our planet’s minerals now corrects that omission. Among its findings is evidence that about half of all mineral diversity is the direct or indirect result of living things and their byproducts. It’s a discovery that could provide valuable insights to scientists piecing together Earth’s complex geological history—and also to those searching for evidence of life beyond this world.
In a pair of papers published on July 1, 2022 in American Mineralogist, researchers Robert Hazen, Shaunna Morrison and their collaborators outline a new taxonomic system for classifying minerals, one that places importance on precisely how minerals form, not just how they look. In so doing, their system acknowledges how Earth’s geological development and the evolution of life influence each other.
Their new taxonomy, based on an algorithmic analysis of thousands of scientific papers, recognizes more than 10,500 different types of minerals. That’s almost twice as many as the roughly 5,800 mineral “species” in the classic taxonomy of the International Mineralogical Association, which focuses strictly on a mineral’s crystalline structure and chemical makeup.
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Morrison and Hazen also identified 57 processes that individually or in combination created all known minerals. These processes included various types of weathering, chemical precipitations, metamorphic transformation inside the mantle, lightning strikes, radiation, oxidation, massive impacts during Earth’s formation, and even condensations in interstellar space before the planet formed. They confirmed that the biggest single factor in mineral diversity on Earth is water, which through a variety of chemical and physical processes helps to generate more than 80 percent of minerals.
But they also found that life is a key player: One-third of all mineral kinds form exclusively as parts or byproducts of living things—such as bits of bones, teeth, coral, and kidney stones (which are all rich in mineral content) or feces, wood, microbial mats, and other organic materials that over geologic time can absorb elements from their surroundings and transform into something more like rock. Thousands of minerals are shaped by life’s activity in other ways, such as germanium compounds that form in industrial coal fires. Including substances created through interactions with byproducts of life, such as the oxygen produced in photosynthesis, life’s fingerprints are on about half of all minerals.
But they also found that life is a key player: One-third of all mineral kinds form exclusively as parts or byproducts of living things—such as bits of bones, teeth, coral, and kidney stones (which are all rich in mineral content) or feces, wood, microbial mats, and other organic materials that over geologic time can absorb elements from their surroundings and transform into something more like rock. Thousands of minerals are shaped by life’s activity in other ways, such as germanium compounds that form in industrial coal fires. Including substances created through interactions with byproducts of life, such as the oxygen produced in photosynthesis, life’s fingerprints are on about half of all minerals.
Historically, scientists “have artificially drawn a line between what is geochemistry and what is biochemistry,” said Nita Sahai, a biomineralization specialist at the University of Akron in Ohio who was not involved in the new research. In reality, the boundary between animal, vegetable, and mineral is much more fluid.
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A new origins-based system for classifying minerals reveals the huge geochemical imprint that life has left on Earth. It could help us identify other worlds with life too: “Life Helps Make Almost Half of All Minerals on Earth,” from @jojofoshosho0 in @QuantaMagazine.
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As we muse on minerals, we might send systemic birthday greetings to Thomas Samuel Kuhn; he was born on this date in 1922. A physicist, historian, and philosopher of science, Kuhn believed that scientific knowledge didn’t advance in a linear, continuous way, but via periodic “paradigm shifts.” Karl Popper had approached the same territory in his development of the principle of “falsification” (to paraphrase, a theory isn’t false until it’s proven true; it’s true until it’s proven false). But while Popper worked as a logician, Kuhn worked as a historian. His 1962 book The Structure of Scientific Revolutions made his case; and while he had– and has— his detractors, Kuhn’s work has been deeply influential in both academic and popular circles (indeed, the phrase “paradigm shift” has become an English-language staple).
“What man sees depends both upon what he looks at and also upon what his previous visual-conception experience has taught him to see.”
Thomas S. Kuhn, The Structure of Scientific Revolutions
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