Posts Tagged ‘Isaac Newton’
“A new scientific truth does not triumph by convincing its opponents and making them see the light, but rather because its opponents eventually die, and a new generation grows up that is familiar with it”*…
It’s very hard, historian of science Benjamin Breen explains, to understand the implications of a scientific revolution as one is living through it…
2023 is shaping up to be an important year in the history of science. And no, I’m not talking about the reputed room-temperature semiconductor LK-99, which seems increasingly likely to be a dud.
Instead, I’m talking about the discoveries you’ll find in Wikipedia’s list of scientific advances for 2023. Here are some examples:
• January: Positive results from a clinical trial of a vaccine for RSV; OpenAI’s ChatGPT enters wide use.
• February: A major breakthrough in quantum computing; announcement of a tiny robot that can clean blood vessels; more evidence for the ability of psychedelics to enhance neuroplasticity; major developments in biocomputers.
• March: OpenAI rolls out GPT-4; continued progress on mRNA vaccines for cancer.
• April: NASA announces astronaut crew who will orbit the moon next year; promising evidence for gene therapy to fight Alzheimer’s.
• May: Scientists use AI to translate brain activity into written words; promising results for a different Alzheimer’s drug; human pangenome sequenced (largely by a team of UCSC researchers — go Banana Slugs!); more good news about the potential of mRNA vaccines for fighting cancer.
And skipping ahead to just the past two weeks:
• nuclear fusion ignition with net energy gain was achieved for the second time
• a radical new approach to attacking cancer tumors entered Phase 1 trials in humans
• and — announced just as I was writing this [in August, 2023] — one of the new crop of weight loss drugs was reported to cut rates of heart attack and stroke in high-risk individuals by 20% (!).
Also in January of 2023: the New York Times asked “What Happened to All of Science’s Big Breakthroughs?”
The headline refers to an article published in Nature which argues that there has been a steady drop in “disruptive” scientific and technological breakthroughs between the years of 1945 and 2010. Basically, it’s a restatement of the concept of a “Great Stagnation” which was proposed by the economist Tyler Cowen in 2011. Though the paper cites everyone from Cowen to Albert Einstein and Isaac Newton, it’s worth noting that it doesn’t cite a single historian of science or technology (unless Alexandre Koyré counts)…
Naturally, as a historian of science and medicine, I think that there really are important things to learn from the history of science and medicine! And what I want to argue for the rest of this post boils down to two specific lessons from that history:
- People living through scientific revolutions are usually unaware of them — and, if they are, they don’t think about them in the same way that later generations do.
- An apparent slowdown in the rate of scientific innovation doesn’t always mean a slowdown in the impacts of science. The history of the first scientific revolution — the one that began in the famously terrible seventeenth century — suggests that the positive impacts of scientific innovation, in particular, are not always felt by the people living throughthe period of innovation. Periods when the pace of innovation appears to slow down may also be eras when society becomes more capable of benefitting from scientific advances by learning how to mitigate previously unforeseen risks.
[… There follows a fascinating look back at the 1660s– the “original” scientific revolution– at Boyle, Newton, at what they hoped/expected, and at how that differed for what their work and that of their colleagues actually yielded. Then the cautionary tale of Thomas Midgley..]
As we appear to be entering a new era of rapid scientific innovation in the 2020s, it is worth remembering that it often takes decades before the lasting social value of a technical innovation is understood — and decades more before we understand its downsides.
In the meantime, I’m pretty psyched about the cancer drugs…
As Thomas Kuhn observed, “The historian of science may be tempted to exclaim that when paradigms change, the world itself changes with them.”
On the difficulty of knowing the outcomes of a scientific revolution from within it: “Experiencing scientific revolutions: the 1660s and the 2020s,” from @ResObscura.
* Max Planck
###
As we try to see, we might spare a thought for William Seward Burroughs; he died on this date in 1898. And inventor who had worked in a bank, he invented the world’s first commercially viable recording adding machine and pioneered of its manufacture. The very successful company that he founded went on to become Unisys, which was instrumental in the development of computing… the implications of which we’re still discovering– and Burroughs surely never saw.
Nor, one reckons, did he imagine that his grandson, William Seward Burroughs II, would become the cultural figure that he did.
“Nothing in life is certain except death, taxes and the second law of thermodynamics”*…
The second law of thermodynamics– asserting that the entropy of a system increases with time– is among the most sacred in all of science, but it has always rested on 19th century arguments about probability. As Philip Ball reports, new thinking traces its true source to the flows of quantum information…
In all of physical law, there’s arguably no principle more sacrosanct than the second law of thermodynamics — the notion that entropy, a measure of disorder, will always stay the same or increase. “If someone points out to you that your pet theory of the universe is in disagreement with Maxwell’s equations — then so much the worse for Maxwell’s equations,” wrote the British astrophysicist Arthur Eddington in his 1928 book The Nature of the Physical World. “If it is found to be contradicted by observation — well, these experimentalists do bungle things sometimes. But if your theory is found to be against the second law of thermodynamics I can give you no hope; there is nothing for it but to collapse in deepest humiliation.” No violation of this law has ever been observed, nor is any expected.
But something about the second law troubles physicists. Some are not convinced that we understand it properly or that its foundations are firm. Although it’s called a law, it’s usually regarded as merely probabilistic: It stipulates that the outcome of any process will be the most probable one (which effectively means the outcome is inevitable given the numbers involved).
Yet physicists don’t just want descriptions of what will probably happen. “We like laws of physics to be exact,” said the physicist Chiara Marletto of the University of Oxford. Can the second law be tightened up into more than just a statement of likelihoods?
A number of independent groups appear to have done just that. They may have woven the second law out of the fundamental principles of quantum mechanics — which, some suspect, have directionality and irreversibility built into them at the deepest level. According to this view, the second law comes about not because of classical probabilities but because of quantum effects such as entanglement. It arises from the ways in which quantum systems share information, and from cornerstone quantum principles that decree what is allowed to happen and what is not. In this telling, an increase in entropy is not just the most likely outcome of change. It is a logical consequence of the most fundamental resource that we know of — the quantum resource of information…
Is that most sacrosanct natural laws, second law of thermodynamics, a quantum phenomenon? “Physicists Rewrite the Fundamental Law That Leads to Disorder,” from @philipcball in @QuantaMagazine.
* “Nothing in life is certain except death, taxes and the second law of thermodynamics. All three are processes in which useful or accessible forms of some quantity, such as energy or money, are transformed into useless, inaccessible forms of the same quantity. That is not to say that these three processes don’t have fringe benefits: taxes pay for roads and schools; the second law of thermodynamics drives cars, computers and metabolism; and death, at the very least, opens up tenured faculty positions.” — Seth Lloyd
###
As we get down with disorder, we might spare a thought for Francois-Marie Arouet, better known as Voltaire; he died on this date in 1778. The Father of the Age of Reason, he produced works in almost every literary form: plays, poems, novels, essays, and historical and scientific works– more than 2,000 books and pamphlets (and more than 20,000 letters). He popularized Isaac Newton’s work in France by arranging a translation of Principia Mathematica to which he added his own commentary.
A social reformer, Voltaire used satire to criticize the intolerance, religious dogma, and oligopolistic privilege of his day, perhaps nowhere more sardonically than in Candide.

“A man will turn over half a library to make one book.”*…

Continuing yesterday’s focus on books…
Marioka Shoten is a bookstore that sells only one book at a time (but sells multiple copies of it) for a week. The bookseller Yoshiyuki Morioka carefully selects a title from novels, manga, biographies and graphic novels for showcasing every week. With the extreme approach to curation, the bookstore is a blend of a shop, a gallery and a meeting place with an essence of minimalism…
From Rishikesh Sreehari (@rishikeshshari), “Single Room with a Single Book,” in his fascinating newsletter 10 + 1 Things.
See also, “Japanese bookshop stocks only one book at a time,” in @guardian.
* Samuel Johnson
###
As we contemplate curation, we might send rational birthday greetings to Francois-Marie Arouet, better known as Voltaire; he was born on this date in 1694. The Father of the Age of Reason, he produced works in almost every literary form: plays, poems, novels, essays, and historical and scientific works– more than 2,000 books and pamphlets (and more than 20,000 letters). He popularized Isaac Newton’s work in France by arranging a translation of Principia Mathematica to which he added his own commentary.
A social reformer, Voltaire used satire to criticize the intolerance, religious dogma, and oligopolistic privilege of his day, perhaps nowhere more sardonically than in Candide.

“Man tends to define in terms of the familiar. But the fundamental truths may not be familiar.”*…
Most of us probably do not need to think too hard to distinguish living things from the “non-living”. A human is alive; a rock is not. Easy!
Scientists and philosophers do not see things quite this clearly. They have spent millennia pondering what it is that makes something alive. Great minds from Aristotle to Carl Sagan have given it some thought – and they still have not come up with a definition that pleases everyone. In a very literal sense, we do not yet have a “meaning” for life.
If anything, the problem of defining life has become even more difficult over the last 100 years or so. Until the 19th Century one prevalent idea was that life is special thanks to the presence of an intangible soul or “vital spark”. This idea has now fallen out of favour in scientific circles. It has since been superseded by more scientific approaches. Nasa, for instance, has described life as “a self-sustaining chemical system capable of Darwinian evolution”.
But Nasa’s is just one of many attempts to pin down all life with a simple description. In fact, over 100 definitions of life have been proposed, with most focusing on a handful of key attributes such as replication and metabolism.
To make matters worse, different kinds of scientist have different ideas about what is truly necessary to define something as alive. While a chemist might say life boils down to certain molecules, a physicist might want to discuss thermodynamics…
A comparative survey of the definitions that currently exist concludes…
To properly define life, we might need to find some aliens.
The irony is that attempts to pin down a definition of life before we discover those aliens might actually make them more difficult to find. What a tragedy it would be if in the 2020s the new Mars rover trundles straight past a Martian, simply because it does not recognise it as being alive.
“The definition can actually hinder the search for novel life,” says [Carol] Cleland. “We need to get away from our current concept, so that we are open to discovering life as we don’t know it.”
It is surprisingly difficult to pin down the difference between living and non-living things: “There are over 100 definitions of ‘life’ and all are wrong.“
* Carl Sagan
###
As we strive for beginner’s mind, we might send exploratory birthday greetings to John Theophilus Desaguliers; he was born on this date in 1683. A natural philosopher, clergyman, and engineer, he is best remembered as the experimental assistant to Isaac Newton, who went on to popularize Newton’s work in public lectures and publications. On the strength of that work, Desaguliers was elected to the Royal Society and ultimately became its curator.
In his own work he coined the terms conductor and insulator. He repeated and extended the work of Stephen Gray in electricity. He proposed a scheme for heating vessels such as salt-boilers by steam instead of fire. And he made inventions of his own (e.g., a planetarium), and material improvements to others’ machines, such as Thomas Savery’s steam engine (by adding a safety valve and using an internal water jet to condense the steam in the displacement chambers) and a ventilator at the House of Commons.







You must be logged in to post a comment.