Posts Tagged ‘genes’
“The world is bound in secret knots”*…
Everyone knows what a knot is. But knots have special significance in math and science because their properties can help unlock secrets hidden within topics ranging as widely as the biochemistry of DNA, the synthesis of new materials, and the geometry of three-dimensional spaces. In his podcast, The Joy of Wh(Y), the sensational Steven Strogatz explores the mysteries of knots with his fellow mathematicians Colin Adams and Lisa Piccirillo…
How do mathematicians distinguish different types of knots? How many different kinds of knots are there? And why do mathematicians and scientists care about knots anyway? Turns out, there’s lots of real-world applications for this branch of math, now called knot theory. It started out with the mystery of the chemical elements about 150 years ago, which were, at the time, thought to be different kinds of knots tied in the ether. Nowadays, knot theory is helping us understand how enzymes can disentangle strands of linked DNA. And also, knot theory has potential in basic research to create new kinds of medicines, including some chemotherapy drugs. But in math itself, knot theory is helping mathematicians work out the riddles of higher-dimensional spaces…
The study of knots unites the interests of researchers in fields from molecular biology to theoretical physics: “Untangling Why Knots Are Important,” from @stevenstrogatz in @QuantaMagazine. Listen here; read the transcript here.
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As we take stock of tangles, we might might send nicely-tied birthday greetings to a beneficiary and user of knot theory, Francis Collins; he was born on this date in 1950. A physician and geneticist, he discovered the genes associated with a number of diseases, led the Human Genome Project, and served as the director of the National Institutes of Health.
“We are a species which is naturally moved by curiosity, the only one left of a group of species (the genus Homo) made up of a dozen equally curious species”*…
… and one thing that curiosity might lead us to wonder is where evolution might take humanity from here. As Nick Longrich points out…
Discussions of human evolution are usually backward looking, as if the greatest triumphs and challenges were in the distant past. But as technology and culture enter a period of accelerating change, our genes will too. Arguably, the most interesting parts of evolution aren’t life’s origins, dinosaurs, or Neanderthals, but what’s happening right now, our present – and our future.
He reasons to some fascinating possibilities…
Humanity is the unlikely result of 4 billion years of evolution.
From self-replicating molecules in Archean seas, to eyeless fish in the Cambrian deep, to mammals scurrying from dinosaurs in the dark, and then, finally, improbably, ourselves – evolution shaped us.
Organisms reproduced imperfectly. Mistakes made when copying genes sometimes made them better fit to their environments, so those genes tended to get passed on. More reproduction followed, and more mistakes, the process repeating over billions of generations. Finally, Homo sapiens appeared. But we aren’t the end of that story. Evolution won’t stop with us, and we might even be evolving faster than ever.
It’s hard to predict the future. The world will probably change in ways we can’t imagine. But we can make educated guesses. Paradoxically, the best way to predict the future is probably looking back at the past, and assuming past trends will continue going forward. This suggests some surprising things about our future…
Meet our future selves: “Future evolution: from looks to brains and personality, how will humans change in the next 10,000 years?“– @NickLongrich in @ConversationUS.
* Carlo Rovelli, Seven Brief Lessons on Physics
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As we ponder the possible, we might send insightful birthday greetings to Richard Dawkins; he was born on this date in 1947. An evolutionary biologist, he made a number of important contributions to the public understanding of evolution. In his 1976 book The Selfish Gene, he popularized the gene-centred view of evolution and introduced the term meme. In The Extended Phenotype (1982), he introduced the influential concept that the phenotypic effects of a gene are not necessarily limited to an organism’s body, but can stretch far into the environment. And in The Blind Watchmaker (1986), he argued against the watchmaker analogy, an argument for the existence of a supernatural creator based upon the complexity of living organisms; instead, he described evolutionary processes as analogous to a blind watchmaker, in that reproduction, mutation, and selection are unguided by any designer.
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