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Posts Tagged ‘diabetes

“Gain not base gains; base gains are the same as losses”*…

When inventor Frederick Banting discovered insulin in 1921, he refused to put his name on the patent. He felt it was unethical for a doctor to profit from a discovery that would save lives. Banting’s co-inventors, James Collip and Charles Best, sold the insulin patent to the University of Toronto for a mere $1. They wanted everyone who needed their medication to be able to afford it. [see here]

Today, Banting and his colleagues would be spinning in their graves: Their drug, which many of the 30 million Americans with diabetes rely on, has become the poster child for pharmaceutical price gouging.

The cost of the four most popular types of insulin has tripled over the past decade, and the out-of-pocket prescription costs patients now face have doubled. By 2016, the average price per month rose to $450 — and costs continue to rise, so much so that as many as one in four people with diabetes are now skimping on or skipping lifesaving doses

Why Americans ration a drug discovered– and given free to the world– in the 1920s: “The absurdly high cost of insulin, explained.”

* Hesiod (See also Proverbs 28:20: “he that maketh haste to be rich shall not be innocent”)

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As we ponder pleonexia, we might send healing birthday greetings to Edward Lawrie Tatum; he was born on this date in 1909. A geneticist, he shared half of the Nobel Prize in Physiology or Medicine in 1958 with George Beadle for showing that genes control individual steps in metabolism. During World War II, his work was of use in maximizing penicillin production, and it has also made possible the introduction of new methods for assaying vitamins and amino acids in foods and tissues. Tatum and Joshua Lederberg (the winner of the other half of the 1958 Nobel award), discovered genetic recombination in bacteria.

His discoveries were made freely available to the scientific community.

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“It was all so very businesslike that one watched it fascinated. It was pork-making by machinery, pork-making by applied mathematics.”*…

 

In the mid-to-late 1800s, the meat industry — from the cowboys and cattle drives to the Chicago slaughterhouses to the refrigerated railcars delivering steaks to New York’s finest restaurants — was the largest industry in America. At the heart of this industry were entrepreneurs like Philip Danforth Armour and Gustavus Franklin Swift, who pioneered business practices later adopted by the automobile industry and whose company names survive to this day:

“[In the meat industry in the mid-1800s], automation was the secret ingredient. Overhead wheels were introduced to carry the hog or the steer from one fixed worksta­tion to the next. Before long, this approach evolved into an over­head trolley system driven by steam engines and industrial belts. Specific repetitive tasks were assigned to each worker along what became, in effect, the first assembly line, although the actual work was disassembly. It was from studying this process in the Chicago slaughterhouses that Henry Ford came up with his own method for assembling automobiles — a development that would revolutionize mass manufacturing…

More at “The American Meat Colossus,” an excerpt from Cattle Kingdom: The Hidden History of the Cowboy West, by Christopher Knowlton.

* “It was all so very businesslike that one watched it fascinated. It was pork-making by machinery, pork-making by applied mathematics. And yet somehow the most matter-of-fact person could not help thinking of the hogs; they were so innocent, they came so very trustingly; and they were so very human in their protests – and so perfectly within their rights! They had done nothing to deserve it; and it was adding insult to injury, as the thing was done here, swinging them up in this cold-blooded, impersonal way, without pretence at apology, without the homage of a tear.”  – Upton Sinclair (author of The Jungle)

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As we ponder protein, we might recall that it was on this date in 1921 that Canadians Sir Frederick Banting and his assistant Charles Best isolated insulin (from canine subjects).  Later that year, working with a University of Toronto colleague,  J.J.R. MacLeod, Banting developed a diabetes treatment for humans– for which he and MacLeod shared the Nobel Prize in Medicine.  Banting and Best (with whom he shared his Nobel Prize money) later improved both the sourcing process for insulin (discovering how to extract it from an intact pancreas) and the diabetes detection process.

Best (left) and Bantling with with one of the diabetic dogs used in their experiments with insulin

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Written by LW

July 27, 2017 at 1:01 am

When hunger won’t wait…

 

“For when you need a snack before tonight’s suicide attempt…”

From LiarTownUSA, via the always-riveting Richard Kadrey’s Damn Tumblr.

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As we contemplate culinary curiosity, we might send prickly birthday greetings to James Bertram Collip; he was born on this date in 1892.  A pioneering endocrinologist, Collip was a leader of the Toronto team that isolated insulin (in 1921) and developed it for clinical use.  Later in his career he isolated the parathyroid hormone and established a bioassay for measuring serum calcium.

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Written by LW

November 20, 2013 at 1:01 am

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