Posts Tagged ‘scientific research’
“When you mix science and politics, you get politics:*…

Tina Hesman Saey on a looming threat to the U.S…
Soviet scientists in the 1930s knew what could happen if they bucked the party line: denunciation, firing and banishment from the scientific establishment, even imprisonment and death. Political reprisals against those who opposed the views of dictator Joseph Stalin and his followers — and the dubious science they endorsed — led to the starvation of millions, as well as to decades of lost progress in fields from agriculture to molecular biology.
Now, scientists are warning that history could repeat itself — but in the United States.
A new proposal from the U.S. Office of Management and Budget would put political appointees in charge of funding decisions traditionally overseen by scientists. In recent years, the federal government has funded about 40 percent of basic science research in the United States.
The OMB’s more than 400-page proposed rule change would let political appointees decide how to hand out federal research funds and who can get them. It would cut funding for collaboration with scientists in other countries and restrict scientists’ ability to communicate their findings. What’s more, it could prevent research on matters that President Donald Trump’s administration has deemed “not in the national interest” — such as studies on health disparities, mRNA-based vaccines and research that doesn’t recognize biological sex as a strict binary.
The new rules would also give OMB the power to rescind previously approved research funds. The proposal “poses a sweeping threat to federal grantmaking and the responsible stewardship of American taxpayer dollars,” the science advocacy group Stand Up for Science Foundation said in a report. In addition, it would impact nonscientific grants supporting services for mental health, housing, education, veterans and Tribal nations, affecting the health and well-being of millions.
So far, OMB has received more than 98,000 comments on the proposal. The public comment period closes July 13. It then will be up to OMB to decide whether to keep the rule as is, revise it or scrap it.
These far-reaching measures are already drawing parallels to dark moments in scientific history. Some researchers say the recent mass firings, policy changes and grant cancellations at federal research institutions, including the U.S. National Institutes of Health and Centers for Disease Control and Prevention, closely mirror what happened in the U.S.S.R. under Stalin. “A similar threat now hangs over U.S. science,” the editorial board of The New England Journal of Medicine wrote in June.
Its editorial invoked the example of Trofim Lysenko [see here], an agronomist and astute political operator who rose to power in the 1930s Soviet Union under Stalin.
Until the 1930s, “the Soviet Union was a real powerhouse in the field of genetics,” says Lee Dugatkin, an evolutionary biologist and historian of science at the University of Louisville in Kentucky.
Then, Lysenko came along. “This guy was your sort of classic charlatan,” Dugatkin says. “He had the equivalent of a mail order degree in agriculture, but he was quite good with the press, and he started to basically spread this idea out there that he was capable of dramatically increasing crop yield, particularly wheat.”
Lysenko’s supposed innovation was a process called vernalization and amounted to soaking seeds in freezing water. The resulting plants — and all their offspring — should be resistant to the U.S.S.R.’s famously cold winters, Lysenko reasoned.
His reasoning was based on a disproven idea in evolutionary biology called Lamarckian inheritance. French biologist Jean-Baptiste Lamarck and his followers thought that things an organism experiences in its lifetime can be handed down to the next generation. The classic example is a giraffe that has to stretch to reach leaves producing offspring with long necks.
This idea ran counter to Mendelian genetics, which holds that genes — not environmental influences — control traits and are passed to offspring. Mendelian geneticists thought it would take five years to breed more cold-tolerant crops. Lysenko said he could do it in two to three years.
Stalin didn’t have time to wait. He was trying to get collective farms going and needed to increase crop yields to feed more than 150 million people. Large parts of the country had already suffered from famine in 1932 and 1933 and about 6 million people died. Some resorted to cannibalism.
Stalin embraced Lysenko’s quick-fix approach. That decision, says Michael Gordin, a historian of science at Princeton University, was “something that the majority of people at the time, and everyone since, considers the wrong side of the dispute.”
Lysenko was put in charge of a prestigious genetics institute and forced his scientifically unsound farming practices on the collective farms. His methods were disastrous.
Soaking seeds in freezing water hampered germination, leading to crop losses. Millions starved. Meanwhile, Mendelian genetics was branded a “whore of capitalism,” and geneticists were forced to renounce their views or lose their jobs. Many were jailed, and almost a dozen were executed or died in prison.
The Soviet Union lost its scientific leadership role and sat on the sidelines for important scientific discoveries of the 1950s and beyond. One, Gordin says, was the development of “massively” productive hybrid corn. The country also missed out on the discovery of DNA and the advent of molecular biology, putting Soviet genetics decades behind the rest of the world.
Soviet genetics did not recover from Lysenko’s influence until after the break-up of the Soviet Union in the late 1980s and early 1990s, Gordin says. “I think you’d be hard pressed to find anybody who thinks that … Russia is today, or Ukraine, or any post-Soviet successor state, is a leading molecular biology country.”…
The Soviets did it, and it didn’t end well: “Here’s what happens when you put politicians in charge of science,” from @thsaey.bsky.social in @sciencenews.bsky.social.
See also: Idiocracy
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As we remember the past so as not to repeat it, we might recall that it was on this date in 1834 that the Spanish Inquisition (finally) ended. Authorized by Pope Sixtus IV in 1478, the Inqusition was initially led by inquisitors (Miguel de Morillo and Juan de San Martín) who were appointed by the future Catholic monarchs, King Ferdinand II of Aragon and Queen Isabella I of Castile. It was originally (ostensibly) intended primarily to identify heretics; its aim, to maintain Christian orthodoxy. But it became an effective instrument of state power by replacing the Medieval Inquisition, which was under Papal control.
Over its course, the Inquisition prosecuted an estimated 150,000 people for various offences. An estimated 3,000–5,000 were turned over to the state for execution, particularly in the initial 50 years, mostly by burning at the stake. Other punishments included penance and public flogging, exile, enslavement on galleys, and prison terms ranging from several years to life. In many of these punishments an important motive was the confiscation of all the victims’ property.
As Monty Python observed, “nobody expects the Spanish Inquisition.” And nobody expected it to last 356 years.

“Any fool can know. The point is to understand.”*…
… and, Rachael Scarborough King and Seth Rudy argue, to serve a clear purpose…
Right now, many forms of knowledge production seem to be facing their end. The crisis of the humanities has reached a tipping point of financial and popular disinvestment, while technological advances such as new artificial intelligence programmes may outstrip human ingenuity. As news outlets disappear, extreme political movements question the concept of objectivity and the scientific process. Many of our systems for producing and certifying knowledge have ended or are ending.
We want to offer a new perspective by arguing that it is salutary – or even desirable – for knowledge projects to confront their ends. With humanities scholars, social scientists and natural scientists all forced to defend their work, from accusations of the ‘hoax’ of climate change to assumptions of the ‘uselessness’ of a humanities degree, knowledge producers within and without academia are challenged to articulate why they do what they do and, we suggest, when they might be done. The prospect of an artificially or externally imposed end can help clarify both the purpose and endpoint of our scholarship.
We believe the time has come for scholars across fields to reorient their work around the question of ‘ends’. This need not mean acquiescence to the logics of either economic utilitarianism or partisan fealty that have already proved so damaging to 21st-century institutions. But avoiding the question will not solve the problem. If we want the university to remain a viable space for knowledge production, then scholars across disciplines must be able to identify the goal of their work – in part to advance the Enlightenment project of ‘useful knowledge’ and in part to defend themselves from public and political mischaracterisation.
Our volume The Ends of Knowledge: Outcomes and Endpoints Across the Arts and Sciences (2023) asks how we should understand the ends of knowledge today. What is the relationship between an individual knowledge project – say, an experiment on a fruit fly, a reading of a poem, or the creation of a Large Language Model – and the aim of a discipline or field? In areas ranging from physics to literary studies to activism to climate science, we asked practitioners to consider the ends of their work – its purpose – as well as its end: the point at which it might be complete. The responses showed surprising points of commonality in identifying the ends of knowledge, as well as the value of having the end in sight…
Read on for a provocative case that academics need to think harder about the purpose of their disciplines and a consideration of whether some of those should come to an end: “The Ends of Knowledge,” in @aeonmag.
* Albert Einstein
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As we contemplate conclusions, we might recall that it was on this date in 1869 that the first issue of the journal Nature was published. Taking it’s title from a line of Wordsworth’s (“To the solid ground of nature trusts the Mind that builds for aye”), its aim was to “provide cultivated readers with an accessible forum for reading about advances in scientific knowledge.” It remains a weekly, international, interdisciplinary journal of science, one of the few remaining that publish across a wide array of fields. It is consistently ranked the world’s most cited scientific journal and is ascribed an impact factor of approximately 64.8, making it one of the world’s top academic journals.

“Only two things are infinite, the universe and human stupidity; and I’m not sure about the former”*…
Figure 1. Screenshot of a video of a Golden Retriever chasing its tail on YouTube™.
“Tail-chasing is widely celebrated as normal canine behaviour in cultural references. However, all previous scientific studies of tail-chasing or ‘spinning’ have comprised small clinical populations of dogs with neurological, compulsive or other pathological conditions; most were ultimately euthanased. Thus, there is great disparity between scientific and public information on tail-chasing. I gathered data on the first large (n = 400), non-clinical tail-chasing population, made possible through a vast, free, online video repository, YouTube™…” (more…)
Meredith Carpenter and Lillian Fritz-Laylin, “two prone-to-distraction grad students,” are NCBI-ROFL (National Center for Biotechnology Information- Roll on the Floor Laughing), the source of a daily blog, nestled in the Discoblog section of Discover.com. Day in, day out, they post what they describe (with estimable understatement) as “real scientific papers with funny subjects”… like the one above.
For a quick– and enormously entertaining– survey of the sorts of research they’ve uncovered, readers should view this presentation (from O’Reilly Media’s Ignite Sci FOO, 2011):
*Albert Einstein
As we rethink our dissertation topics, we might send carefully deduced birthday wishes to criminologist Dr. Henry Chang-Yu Lee; he was born on this date in 1938 in Rugao city, Jiangsu province, China, and fled to Taiwan at the end of the Chinese Civil War in the late 1940s. He entered the police force there, and rose to the rank of Captain before coming to the U.S. in 1972. He studied forensics at John Jay College, then biochemistry at NYU– after which he moved into law enforcement in Connecticut, where he became Director, Connecticut State Police Forensic Science Laboratory and Chief of the Division of Scientific Services and Chief Criminologist of the State.
Dr. Lee has authored or co-authored of 30 books and over 300 articles, for most part academic forensics works; but of late, “true crime”: after his retirement some years ago, Dr. Lee turned to consulting, mostly to criminal defense teams, on high profile cases (O.J. Simpson, Jon-Benet Ramsey, Laci Peterson), and on investigations of note (Vince Foster, 9/11)… stories he also recounts on his TruTV series, Trace Evidence: The Case Files of Dr. Henry Lee. While Dr. Lee and his work remain widely respected, he is not without controversy: In 2007, Los Angeles County Superior Court Judge Larry Paul Fidler, the judge in the Phil Spector murder trial, said that he had concluded Dr. Henry Lee hid or accidentally destroyed a piece of evidence from the scene of actress Lana Clarkson’s shooting.



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