(Roughly) Daily

Posts Tagged ‘cytology

“A world that is safe for mothers is safe for all”*…

A new mother joyfully holds her newborn baby in a hospital setting, both smiling and looking content.

There’s much discussion today of falling fertility rates and the prospect of a shrinking population. In her terrific newsletter, Your Local Epidemiologist, Katelyn Jetelina explores the (real) reasons why, and what can be done…

In the U.S.—and across much of the world—fertility rates are falling, and populations are projected to shrink.

A line graph illustrating the total fertility rate (births per woman) over time, showing a decline in the United States (in red) and globally (in blue) from 1933 to 2023.

The reasons people are worried vary. Some fear a loss of global influence or long-term human survival. Others approach the issue through religious, political, or ideological lenses—or just out of curiosity. Whatever the motivation, the question keeps coming up: What can we do?

In response, the new administration—guided in part by Project 2025—is considering financial incentives to encourage people to have more children. Ideas include education, like on menstrual cycles, or a “National Medal of Motherhood” to mothers with six or more children, as well as financial incentives like a $5,000 cash baby bonus or Fulbright scholarships reserved for mothers.

Globally, paying families to have children has yielded mixed results. In Russia, for example, payments ($10,000) have increased fertility rates by about 20%. However, in Canada during the 1970s, similar efforts yielded only a short-term increase.

So no—we don’t need to blindly throw spaghetti at the wall. We have the evidence: if we want people to have more children, we need to create a society that actually supports parents…

[Jetelina unpacks the dynamics at play: access to affordable health care, the lack of support for new parents, the cost of raising a child, the climate of fear of maternal mortality, and the dismantling of programs that support women…]

… People aren’t having fewer children because they don’t care about family, faith, or their future, or the future of this country. They’re having fewer because the system makes it too hard, too risky, and too expensive. A $5,000 payment is a drop in the bucket compared to what is required of families in this day and age.

If the government wants to be part of the solution, it shouldn’t just throw out incentives. It should invest in the foundation: affordable care, parental leave, safe childbirth, and supportive systems.

Let’s focus on what matters: building a society where families can thrive. If we do that, everything else—including birth rates—may just follow…

It’s not rocket science: “Birth rates are falling. But solutions are focused on the wrong thing,” from @kkjetelina.bsky.social.

(Image at top: source)

Abhijit Naskar (@naskarism.bsky.social)

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As noodle on nativity, we might spare a thought for Edouard Van Beneden; he died on this date in 1910. An embryologist, cytologist and marine biologist, he made discoveries concerning fertilization in sex cells and chromosome numbers in body cells. His studies (of the roundworm Ascaris) showed that sexual fertilization results from the union of two different cell half-nuclei. Thus a new single cell is created with its number of chromosomes derived as one-half from the male sperm and the other half from the female egg. Van Beneden also determined that the chromosome number is constant for every body cell of a species. His theory of embryo formation in mammals became a standard scientific principle.

Statue of Edouard Van Beneden, an embryologist and marine biologist, displayed outside a building, with an inscription detailing his name and lifespan.
Edouard van Beneden in front of the Aquarium et musee de zoologie in Liège, Belgium (source)

“Every living thing is made of cells, and everything a living thing does is done by the cells that make it up”*…

And so, as Charudatta Navare explains, we need to be thoughtful about how we talk about them, as prevailing scientific narratives project human social hierarchies onto nature in misleading ways…

When you think about it, it is amazing that something as tiny as a living cell is capable of behaviour so complex. Consider the single-cell creature, the amoeba. It can sense its environment, move around, obtain its food, maintain its structure, and multiply. How does a cell know how to do all of this? Biology textbooks will tell you that each eukaryotic cell, which constitutes a range of organisms from humans to amoeba, contains a control centre within a structure called the nucleus. Genes present in the nucleus hold the ‘information’ necessary for the cell to function. And the nucleus, in turn, resides in a jelly-like fluid called the cytoplasm. Cytoplasm contains the cellular organelles, the ‘little organs’ in the cell; and these organelles, the narrative goes, carry out specific tasks based on instructions provided by the genes.

In short, the textbooks paint a picture of a cellular ‘assembly line’ where genes issue instructions for the manufacture of proteins that do the work of the body from day to day. This textbook description of the cell matches, almost word for word, a social institution. The picture of the cytoplasm and its organelles performing the work of ‘manufacturing’, ‘packaging’ and ‘shipping’ molecules according to ‘instructions’ from the genes eerily evokes the social hierarchy of executives ordering the manual labour of toiling masses. The only problem is that the cell is not a ‘factory’. It does not have a ‘control centre’. As the feminist scholar Emily Martin observes, the assumption of centralised control distorts our understanding of the cell.

A wealth of research in biology suggests that ‘control’ and ‘information’ are not restricted at the ‘top’ but present throughout the cell. The cellular organelles do not just form a linear ‘assembly line’ but interact with each other in complex ways. Nor is the cell obsessed with the economically significant work of ‘manufacturing’ that the metaphor of ‘factory’ would have us believe. Instead, much of the work that the cell does can be thought of as maintaining itself and taking ‘care’ of other cells.

Why, then, do the standard textbooks continue to portray the cell as a hierarchy? Why do they invoke a centralised authority to explain how each cell functions? And why is the imagery so industrially loaded?…

We need better metaphors to describe cellular life: “The cell is not a factory,” from @charudatta_n in @aeonmag.

* cytologist and author L.L. Larison Cudmore

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As we avoid anthropomorphism, we might recall that it was on this date in 1981 that the first patent for a life form (U.S. No. 4,259,444) was issued to Ananda Chakrabarty (who had done his research at GE). Chakrabarty had developed Pseudomonas bacterium (now called Burkholderia cepacia) which can be used to clean up toxic spills (as it can break down crude oil into simpler substances that can even become food for aquatic life)– an ability possessed by no naturally occurring bacteria.

The application had been originally denied by the patent office, on the grounds that under patent law at that time, living things were generally understood to not be patentable subject matter under 35 U.S.C. § 101.

Chakrabarty (and GE) appealed (to the Board of Patent Appeals and Interferences), lost, and appealed again ( the United States Court of Customs and Patent Appeals) and prevailed…. At which point, the Patent Office (led by director Sydney Diamond) appealed in civil court.

Ultimately, the Supreme Court ruled (5-4, Diamond v. Chakrabarty) in Chakrabarty’s favor. As Chief Justice Warren Burger wrote for the majority, life can be patented if they are the outcome of “human ingenuity and research” and not “nature’s handiwork”– a ruling that cleared the way for patents to be issued on genetically-engineered mice and other animals, seeds, and more.

Chakrabarty (source)

Written by (Roughly) Daily

March 31, 2024 at 1:00 am